Hepatoma
Primary tumor (T)
• TX: Primary tumor cannot be assessed
• T0: No evidence of primary tumor
• T1: Solitary tumor without vascular invasion
• T2: Solitary tumor with vascular invasion or multiple tumors none more than 5 cm
• T3: Multiple tumors more than 5 cm or tumor involving a major branch of the portal or hepatic vein(s)
• T4: Tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of the visceral peritoneum
Regional lymph nodes (N)
• NX: Regional lymph nodes cannot be assessed
• N0: No regional lymph node metastasis
• N1: Regional lymph node metastasis
[Note: The regional lymph nodes are the hilar (i.e., those in the hepatoduodenal ligament, hepatic, and periportal nodes). Regional lymph nodes also include those along the inferior vena cava, hepatic artery, and portal vein. Any lymph node involvement beyond these nodes is considered distant metastasis and should be coded as M1. Involvement of the inferior phrenic lymph nodes should also be considered M1.
Distant metastasis (M)
• MX: Distant metastasis cannot be assessed
• M0: No distant metastasis
• M1: Distant metastasis
Exterahepatic Toumor
• TX: Primary tumor cannot be assessed
• T0: No evidence of primary tumor
• Tis: Carcinoma in situ
• T1: Tumor confined to the bile duct histologically
• T2: Tumor invades beyond the wall of the bile duct
• T3: Tumor invades the liver, gallbladder, pancreas, and/or unilateral branches of the portal vein (right or left) or hepatic artery (right or left)
• T4: Tumor invades any of the following: main portal vein or its branches bilaterally, common hepatic artery, or other adjacent structures, such as the colon, stomach, duodenum, or abdominal wall
Regional lymph nodes (N)
• NX: Regional lymph nodes cannot be assessed
• N0: No regional lymph node metastasis
• N1: Regional lymph node metastasis
Distant metastasis (M)
• MX: Distant metastasis cannot be assessed
• M0: No distant metastasis
• M1: Distant metastasis
AJCC stage groupings
Stage 0
• Tis, N0, M0
Stage IA
• T1, N0, M0
Stage IB
• T2, N0, M0
Stage IIA
• T3, N0, M0
Stage IIB
• T1, N1, M0
• T2, N1, M0
• T3, N1, M0
Stage III
• T4, any N, M0
Stage IV
• Any T, any N, M1
